Palbociclib-propargyl

PG-20161-15888

Product information

Catalog No.
PG-20161-15888
Product Name
Palbociclib-propargyl
CAS No.
2366269-23-8
Molecular Formula
C27H31N7O2
Molecular Weight
485.6
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

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Packaging & pricing

Packaging and pricing for PG-20161-15888
Catalog No.PackagingPrice (USD)StockInquiry action
PG-20161-1588810 MGUSD 349In stock
PG-20161-1588825 MGUSD 503In stock
PG-20161-1588850 MGUSD 1,002In stock
PG-20161-15888100 MGUSD 1,167In stock

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General Information

Product Name
Palbociclib-propargyl
CAS No.
2366269-23-8
Synonyms
Not specified
Molecular Formula
C27H31N7O2
Molecular Weight
485.6
Appearance
Not specified
Solubility
Not specified
Description

Palbociclib-propargyl is a CDK6-targeting ligand used in PROTAC construction. Its alkyne group provides a site for copper-catalyzed azide-alkyne cycloaddition with azide-bearing molecules. It can be connected to a CRBN ligand through a PEG linker to assemble the PROTAC CP-10. The reported CDK6 DC50 of 2.1 nM applies to CP-10, rather than to Palbociclib-propargyl itself.