A28-C6B2 (10mg/ml solution in ethanol)

PG-20161-17664

Product information

Catalog No.
PG-20161-17664
Product Name
A28-C6B2 (10mg/ml solution in ethanol)
CAS No.
Not specified
Molecular Formula
C41H81NO5
Molecular Weight
668.1
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

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General Information

Product Name
A28-C6B2 (10mg/ml solution in ethanol)
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C41H81NO5
Molecular Weight
668.1
Appearance
Not specified
Solubility
Not specified
Description

A28-C6B2 (10mg/ml solution in ethanol) is an ionizable cationic lipid with pKa = 6.43. It has been used to prepare lipid nanoparticles (LNPs) for mRNA delivery in vivo and is cataloged in the ionizable lipid range under ALC-0315 & Analogs.

Following intravenous administration in mice, LNPs containing A28-C6B2 have been reported to accumulate primarily in the spleen and target F4/80+ macrophages, Cd11c+ dendritic cells and, to a lesser extent, T cells. The listed molecular formula is C41H81NO5, the molecular weight is 668.1, and the storage temperature is -20°C.