Tri-GalNAc -COOH

PG-20161-21302

Product information

Catalog No.
PG-20161-21302
Product Name
Tri-GalNAc -COOH
CAS No.
1953146-81-0
Molecular Formula
C75H134N10O35
Molecular Weight
1736
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

Packaging & pricing

Packaging and pricing for PG-20161-21302
Catalog No.PackagingPrice (USD)StockInquiry action
PG-20161-2130250 MGUSD 948In stock
PG-20161-21302100 MGUSD 1,610In stock

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General Information

Product Name
Tri-GalNAc -COOH
CAS No.
1953146-81-0
Synonyms
Not specified
Molecular Formula
C75H134N10O35
Molecular Weight
1736
Appearance
Not specified
Solubility
Not specified
Description

Tri-GalNAc -COOH is an intermediate for preparing lysosome-targeting chimeras (LYTACs). It contains three GalNAc sugar units joined through acyl-amino chains to an ether linker bearing a terminal carboxylic acid. This terminal group provides a site for functionalization with antibodies or biotin.

The compound has been used to prepare anti-EGFR antibody-functionalized LYTACs that reduced EGFR levels in HepG2 hepatocellular carcinoma cells without affecting total protein levels. Its molecular formula is C75H134N10O35, and its listed molecular weight is 1736.