Alloc-Val-Ala-OH
PG-20161-23053
Product information
- Catalog No.
- PG-20161-23053
- Product Name
- Alloc-Val-Ala-OH
- CAS No.
- 330970-70-2
- Molecular Formula
- C12H20N2O5
- Molecular Weight
- 272.3
- Purity
- Not specified
- Storage
- -20°C
- Shipping
- Ambient Temperature
- Documents
Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.
Packaging & pricing
| Catalog No. | Packaging | Price (USD) | Stock | Inquiry action |
|---|---|---|---|---|
| PG-20161-23053 | 250 MG | USD 6 | In stock | |
| PG-20161-23053 | 500 MG | USD 22 | In stock | |
| PG-20161-23053 | 1 G | USD 17 | In stock |
Prices are shown in USD. Final pricing, package availability and delivery are confirmed with your quotation.
General Information
- Product Name
- Alloc-Val-Ala-OH
- CAS No.
- 330970-70-2
- Synonyms
- Not specified
- Molecular Formula
- C12H20N2O5
- Molecular Weight
- 272.3
- Appearance
- Not specified
- Solubility
- Not specified
- Description
Alloc-Val-Ala-OH is a Val-Ala building block used in the synthesis of Tesirine, a pyrrolobenzodiazepine (PBD) dimer payload for antibody-drug conjugates (ADCs). Its Val-Ala sequence is susceptible to cleavage by Cathepsin B, supporting its placement among cleavable ADC linkers.
The Alloc protecting group withstands treatment with piperidine and TFA and can be removed under mild conditions through palladium-catalyzed allyl transfer. The molecular formula is C12H20N2O5, and the specified storage temperature is -20°C.