PROTAC a-Synuclein/Tau degrader 1

PG-20161-30939

Product information

Catalog No.
PG-20161-30939
Product Name
PROTAC a-Synuclein/Tau degrader 1
CAS No.
3032208-24-2
Molecular Formula
C37H39N5O9S
Molecular Weight
729.8
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

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Packaging and pricing for PG-20161-30939
Catalog No.PackagingPrice (USD)StockInquiry action
PG-20161-309395 MGUSD 380In stock
PG-20161-3093910 MGUSD 604In stock
PG-20161-3093925 MGUSD 899In stock

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General Information

Product Name
PROTAC a-Synuclein/Tau degrader 1
CAS No.
3032208-24-2
Synonyms
Not specified
Molecular Formula
C37H39N5O9S
Molecular Weight
729.8
Appearance
Not specified
Solubility
Not specified
Description

PROTAC a-Synuclein/Tau degrader 1 is a blood-brain barrier-penetrant dual degrader targeting a-synuclein (a-Syn) and tau through the ubiquitin-proteasome system (UPS). Reported DC50 values are 1.57 µM and 4.09 µM for a-Syn and tau, respectively. Binding to a-Syn and tau PFF is reported with KDs of 0.47 and 2.78 µM, respectively. This compound is cataloged within the PROTAC degrader and alpha-Synuclein categories.