3,4-Dibromo-Mal-PEG8-Boc-Amine

PG-20161-40464

Product information

Catalog No.
PG-20161-40464
Product Name
3,4-Dibromo-Mal-PEG8-Boc-Amine
CAS No.
Not specified
Molecular Formula
C27H46Br2N2O12
Molecular Weight
750.5
Purity
98%
Storage
-20°C
Shipping
Ambient Temperature
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General Information

Product Name
3,4-Dibromo-Mal-PEG8-Boc-Amine
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C27H46Br2N2O12
Molecular Weight
750.5
Appearance
Not specified
Solubility
Not specified
Description

3,4-Dibromo-Mal-PEG8-Boc-Amine is a site-specific ADC linker combining a dibromomaleimide group with a Boc-protected amine. The two bromine atoms provide two substitution sites on the dibromomaleimide group. Acidic deprotection releases a free amine that can react with an activated succinimidyl (NHS) ester.

The hydrophilic PEG8 spacer improves aqueous solubility and supports optimization of DMPK properties. Cataloged among maleimide and ADC linkers, the compound has a listed purity of 98% and a storage temperature of -20°C.