AK-1690

PG-20161-50533

Product information

Catalog No.
PG-20161-50533
Product Name
AK-1690
CAS No.
2984505-88-4
Molecular Formula
C51H56F2N5O11PS
Molecular Weight
1016.1
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

Packaging & pricing

Packaging and pricing for PG-20161-50533
Catalog No.PackagingPrice (USD)StockInquiry action
PG-20161-505335 MGUSD 322In stock
PG-20161-5053310 MGUSD 515In stock
PG-20161-5053325 MGUSD 1,207In stock

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General Information

Product Name
AK-1690
CAS No.
2984505-88-4
Synonyms
Not specified
Molecular Formula
C51H56F2N5O11PS
Molecular Weight
1016.1
Appearance
Not specified
Solubility
Not specified
Description

AK-1690 is a selective STAT6-targeting PROTAC degrader with reported DC50=1 nM and a Ki of 6 nM against human STAT6. Its degradation activity involves interaction between STAT6 and cereblon. It is cataloged within the STAT degrader group of PROTAC Linkers.

AK-1690 has been reported to deplete STAT6 protein in mouse liver and lung tissues. Research applications include studies related to leukemia, Hodgkin's lymphoma and follicular lymphoma.