Thalidomide-5-(PEG2-acid)

PG-20161-55247

Product information

Catalog No.
PG-20161-55247
Product Name
Thalidomide-5-(PEG2-acid)
CAS No.
Not specified
Molecular Formula
C21H23N3O9
Molecular Weight
461.4
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

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Packaging and pricing for PG-20161-55247
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General Information

Product Name
Thalidomide-5-(PEG2-acid)
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C21H23N3O9
Molecular Weight
461.4
Appearance
Not specified
Solubility
DMSO, DCM, DMF
Description

Thalidomide-5-(PEG2-acid) is a PROTAC building block comprising an E3 ligase ligand, a PEG spacer and a terminal carboxylic acid. The acid group provides a coupling site for primary amines: activation with a reagent such as HATU enables formation of an amide bond.

The PEG spacer contributes to improved water solubility. Listed solvents are DMSO, DCM, DMF. The molecular formula is C21H23N3O9, and the molecular weight is 461.4.