N-(Mal)-N-(PEG8-Val-Cit-PAB-MMAE)-N-(PEG8-Val-Cit-PAB-Exatecan)
PG-20161-12336
MW 2945.5
Same subcategory
Mal-PEG12-Val-Cit-PAB-Exatecan
PG-20161-57335
Product information
- Catalog No.
- PG-20161-57335
- Product Name
- Mal-PEG12-Val-Cit-PAB-Exatecan
- CAS No.
- Not specified
- Molecular Formula
- C74H102FN9O24
- Molecular Weight
- 1520.7
- Purity
- 95%
- Storage
- -20°C
- Shipping
- Ambient Temperature
- Documents
Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.
Packaging & pricing
| Catalog No. | Packaging | Price (USD) | Stock | Inquiry action |
|---|---|---|---|---|
| PG-20161-57335 | 1 MG | Inquiry | In stock | |
| PG-20161-57335 | 5 MG | Inquiry | In stock | |
| PG-20161-57335 | 10 MG | Inquiry | In stock | |
| PG-20161-57335 | 25 MG | Inquiry | In stock |
Final pricing, package availability and delivery are confirmed with your quotation.
General Information
- Product Name
- Mal-PEG12-Val-Cit-PAB-Exatecan
- CAS No.
- Not specified
- Synonyms
- Not specified
- Molecular Formula
- C74H102FN9O24
- Molecular Weight
- 1520.7
- Appearance
- Not specified
- Solubility
- Water, DMF
- Description
Mal-PEG12-Val-Cit-PAB-Exatecan is a cleavable linker-payload for antibody-drug conjugate research. It combines an exatecan payload with a Val-Cit-PAB segment, a PEG12 chain and a maleimide group. The Val-Cit dipeptide is susceptible to Cathepsin B cleavage, while the maleimide supports conjugation to thiol-containing biomolecules. The PEG12 chain contributes hydrophilicity. Listed solvents are Water, DMF, and the supplied purity is 95%.