Pomalidomide-amido-PEG3-Azide

PG-20161-68437

Product information

Catalog No.
PG-20161-68437
Product Name
Pomalidomide-amido-PEG3-Azide
CAS No.
Not specified
Molecular Formula
C22H26N6O8
Molecular Weight
502.5
Purity
98%
Storage
-20°C
Shipping
Ambient Temperature
Documents

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General Information

Product Name
Pomalidomide-amido-PEG3-Azide
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C22H26N6O8
Molecular Weight
502.5
Appearance
Not specified
Solubility
DCM, DMF, ACN
Description

Pomalidomide-amido-PEG3-Azide combines a pomalidomide component with a PEG3 spacer and an azide group for PROTAC-related conjugation. The pomalidomide component recruits E3 ligase to support protein ubiquitination and subsequent degradation. The azide provides a click-chemistry coupling site for alkyne, DBCO or BCN partners, while the PEG3 spacer contributes aqueous solubility. Listed solvents for solubility are DCM, DMF, ACN, and the stated purity is 98%.