Azide-PEG12-Val-Cit-PAB-MMAE

PG-20161-74667

Product information

Catalog No.
PG-20161-74667
Product Name
Azide-PEG12-Val-Cit-PAB-MMAE
CAS No.
Not specified
Molecular Formula
C85H145N13O25
Molecular Weight
1749.2
Purity
98%
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

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General Information

Product Name
Azide-PEG12-Val-Cit-PAB-MMAE
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C85H145N13O25
Molecular Weight
1749.2
Appearance
Not specified
Solubility
Not specified
Description

Azide-PEG12-Val-Cit-PAB-MMAE is a cleavable linker–payload construct for antibody-drug conjugate (ADC) research. It combines an azido conjugation handle, a cathepsin-sensitive Val-Cit dipeptide, a self-immolative PAB linker and the cytotoxic MMAE payload. The azido group supports click conjugation with alkyne-functionalized molecules, while the Val-Cit segment provides a cleavage site for intracellular payload release.

The PEG12 linkage enhances solubility in aqueous media. The listed molecular weight is 1749.2, purity is 98%, and storage temperature is -20°C.