SOS1 activator 1

PG-20161-74941

Product information

Catalog No.
PG-20161-74941
Product Name
SOS1 activator 1
CAS No.
2245237-53-8
Molecular Formula
C26H32ClFN6
Molecular Weight
483
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

Packaging & pricing

Packaging and pricing for PG-20161-74941
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PG-20161-749411 MGUSD 503In stock

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General Information

Product Name
SOS1 activator 1
CAS No.
2245237-53-8
Synonyms
Not specified
Molecular Formula
C26H32ClFN6
Molecular Weight
483
Appearance
Not specified
Solubility
Not specified
Description

SOS1 activator 1 is a benzimidazole derivative that activates SOS1, with a Kd of 44 nM. It increases RAS-GTP activation and modulates ERK phosphorylation, supporting its use in cancer research. It can also serve as a target ligand in PROTAC synthesis, including PROTAC SOS1 degrader-1, for inducing SOS1 degradation. The compound is classified among ligands in the PROTAC linker catalog.