JB170

PG-20161-74973

Product information

Catalog No.
PG-20161-74973
Product Name
JB170
CAS No.
2705844-82-0
Molecular Formula
C48H44ClFN8O11
Molecular Weight
963.4
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

Packaging & pricing

Packaging and pricing for PG-20161-74973
Catalog No.PackagingPrice (USD)StockInquiry action
PG-20161-749731 MGUSD 115In stock
PG-20161-749735 MGUSD 122In stock
PG-20161-7497310 MGUSD 207In stock
PG-20161-7497325 MGUSD 415In stock

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General Information

Product Name
JB170
CAS No.
2705844-82-0
Synonyms
Not specified
Molecular Formula
C48H44ClFN8O11
Molecular Weight
963.4
Appearance
Not specified
Solubility
Not specified
Description

JB170 is an AURORA-A-targeting PROTAC degrader that links Alisertib to the Cereblon-binding molecule Thalidomide. It preferentially binds AURORA-A over AURORA-B and induces S-phase arrest through targeted depletion of AURORA-A. Its activity also includes inhibition of AURORA-A non-catalytic functions. This reagent-grade compound is intended only for laboratory research and is listed within the AURORA degrader category.