PROTAC HER2 degrader-1

PG-20161-80513

Product information

Catalog No.
PG-20161-80513
Product Name
PROTAC HER2 degrader-1
CAS No.
2897640-93-4
Molecular Formula
C49H55N11O7
Molecular Weight
910.1
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

Packaging & pricing

Packaging and pricing for PG-20161-80513
Catalog No.PackagingPrice (USD)StockInquiry action
PG-20161-805131 MGUSD 438In stock

Prices are shown in USD. Final pricing, package availability and delivery are confirmed with your quotation.

Your inquiry

Choose a package above to start your inquiry.

View inquiry (0)

General Information

Product Name
PROTAC HER2 degrader-1
CAS No.
2897640-93-4
Synonyms
Not specified
Molecular Formula
C49H55N11O7
Molecular Weight
910.1
Appearance
Not specified
Solubility
Not specified
Description

PROTAC HER2 degrader-1 is a selective HER2-targeting PROTAC used in research on HER2-positive cancers. It has a reported DC50 of 69 nM and Dmax of 96%. Persistent HER2 degradation is associated with inhibition of downstream AKT and ERK pathways, reduced HER2-positive cell proliferation and tumor growth, and induction of apoptosis in BT-474 cells. Its molecular formula is C49H55N11O7, with a molecular weight of 910.1.