7-O-(Cbz-N-amido-PEG4)- paclitaxel

PG-20161-93557

Product information

Catalog No.
PG-20161-93557
Product Name
7-O-(Cbz-N-amido-PEG4)- paclitaxel
CAS No.
Not specified
Molecular Formula
C66H78N2O21
Molecular Weight
1235.4
Purity
98%
Storage
-20°C
Shipping
Ambient Temperature
Documents

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General Information

Product Name
7-O-(Cbz-N-amido-PEG4)- paclitaxel
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C66H78N2O21
Molecular Weight
1235.4
Appearance
Not specified
Solubility
Not specified
Description

7-O-(Cbz-N-amido-PEG4)- paclitaxel is an ADC payload conjugate combining paclitaxel with a Cbz-protected amido-PEG4 spacer at the 7-O position. The Cbz-protected amine can be removed under acidic conditions, and the PEG spacer improves compatibility with aqueous media. Paclitaxel acts as a microtubule polymer stabilizer and antimicrotubule agent that inhibits cell division, and the compound may be used in antibody-drug conjugate research.