SH-PEG-NH2.HCl

PG-20161-97678

Product information

Catalog No.
PG-20161-97678
Product Name
SH-PEG-NH2.HCl
CAS No.
Not specified
Molecular Formula
Not specified
Molecular Weight
Not specified
Purity
≥95%
Storage
Store at -5°C,keep in dry and avoid sunlight.
Shipping
Not specified
Documents

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General Information

Product Name
SH-PEG-NH2.HCl
CAS No.
Not specified
Synonyms
Thiol-PEG-Amine.HCl | HS-PEG-NH2.HCI | Amino-PEG-Thiol
Molecular Formula
Not specified
Molecular Weight
Not specified
Appearance
Not specified
Solubility
Not specified
Description

SH-PEG-NH2.HCl is a linear heterobifunctional PEGylation reagent with a thiol group and an amine moiety, also referred to as Thiol-PEG-Amine.HCl. The amine forms stable amide bonds with carboxyl groups and reactive NHS esters at pH 7–8.5, while the thiol reacts with maleimide to form thioether bonds at pH 6.5–7.5 and exhibits high affinity for gold surfaces. It is used to modify proteins, peptides, small molecules, and gold-based materials, and PEGylation can improve solubility and stability, reduce immunogenicity of proteins and peptides, and inhibit non-specific binding of charged molecules on modified surfaces.