Duocarmycin SA
PG-20161-19262
Product information
- Catalog No.
- PG-20161-19262
- Product Name
- Duocarmycin SA
- CAS No.
- 130288-24-3
- Molecular Formula
- C25H23N3O7
- Molecular Weight
- 477.5
- Purity
- Not specified
- Storage
- -20°C
- Shipping
- Ambient Temperature
- Documents
Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.
Packaging & pricing
| Catalog No. | Packaging | Price (USD) | Stock | Inquiry action |
|---|---|---|---|---|
| PG-20161-19262 | 1 MG | USD 1,005 | In stock |
Prices are shown in USD. Final pricing, package availability and delivery are confirmed with your quotation.
General Information
- Product Name
- Duocarmycin SA
- CAS No.
- 130288-24-3
- Synonyms
- Not specified
- Molecular Formula
- C25H23N3O7
- Molecular Weight
- 477.5
- Appearance
- Not specified
- Solubility
- Not specified
- Description
Duocarmycin SA is an antitumor antibiotic classified in the duocarmycin ADC payload category. It irreversibly alkylates DNA in the minor groove with sequence selectivity, producing cytotoxic effects through covalent DNA modification. Reported potency is IC₅₀ = 10 pM.
The compound is described as orally bioavailable and has shown synergistic effects with proton radiation in glioblastoma multiforme (GBM) cells in vitro. Its molecular formula is C25H23N3O7, and the listed storage condition is -20°C.