Duocarmycin DM
PG-20161-31223
Product information
- Catalog No.
- PG-20161-31223
- Product Name
- Duocarmycin DM
- CAS No.
- 1116745-06-2
- Molecular Formula
- C26H26ClN3O3
- Molecular Weight
- 464
- Purity
- Not specified
- Storage
- -20°C
- Shipping
- Ambient Temperature
- Documents
Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.
Packaging & pricing
| Catalog No. | Packaging | Price (USD) | Stock | Inquiry action |
|---|---|---|---|---|
| PG-20161-31223 | 1 MG | USD 239 | In stock | |
| PG-20161-31223 | 5 MG | USD 718 | In stock |
Prices are shown in USD. Final pricing, package availability and delivery are confirmed with your quotation.
General Information
- Product Name
- Duocarmycin DM
- CAS No.
- 1116745-06-2
- Synonyms
- Not specified
- Molecular Formula
- C26H26ClN3O3
- Molecular Weight
- 464
- Appearance
- Not specified
- Solubility
- Not specified
- Description
Duocarmycin DM is a cytotoxic payload used in antibody-drug conjugates (ADCs) and acts through DNA minor-groove alkylation. Its curved indole-based structure and reactive spirocyclopropylcyclohexadienone electrophile enable sequence-selective DNA alkylation, which underlies its anticancer activity. Cataloged in the duocarmycin ADC payload group, the compound has the molecular formula C26H26ClN3O3 and a molecular weight of 464. The listed storage temperature is -20°C.