IR-117-17 (solution in ethanol)

PG-20161-25711

Product information

Catalog No.
PG-20161-25711
Product Name
IR-117-17 (solution in ethanol)
CAS No.
Not specified
Molecular Formula
C59H110N2O5
Molecular Weight
927.5
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

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Packaging & pricing

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General Information

Product Name
IR-117-17 (solution in ethanol)
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C59H110N2O5
Molecular Weight
927.5
Appearance
Not specified
Solubility
Not specified
Description

IR-117-17 (solution in ethanol) contains an ionizable, cationic and biodegradable amino lipid used in lipid nanoparticle (LNP) formulations. It is cataloged within the ionizable lipid range.

In mouse studies, nebulized LNPs containing IR-117-17, 1,2-dioleoyl-2-trimethylammoniumpropane (1,2-DOTAP) and other components carried reporter mRNA and produced luciferase luminescence in the lungs and nasal passages. Related nebulized formulations carrying Cre mRNA produced Cre expression in large and small airway cells, alveolar macrophages and epithelial cells in Ai14 mice.