DBCO-PEG2-Val-Cit-PAB-Exatecan

PG-20161-35709

Product information

Catalog No.
PG-20161-35709
Product Name
DBCO-PEG2-Val-Cit-PAB-Exatecan
CAS No.
Not specified
Molecular Formula
C69H75FN10O14
Molecular Weight
1287.4
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
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General Information

Product Name
DBCO-PEG2-Val-Cit-PAB-Exatecan
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C69H75FN10O14
Molecular Weight
1287.4
Appearance
Not specified
Solubility
DMSO, DMF
Description

DBCO-PEG2-Val-Cit-PAB-Exatecan is a cleavable ADC linker incorporating an exatecan payload, a PAB moiety and a cathepsin-cleavable Val-Cit dipeptide. Its DBCO group provides a click chemistry handle for reaction with azide groups, while the PEG2 chain increases the compound’s hydrophilicity. The compound is soluble in DMSO and DMF and has the molecular formula C69H75FN10O14, with a molecular weight of 1287.4.