DBCO-PEG8-Val-Cit-PAB-Exatecan

PG-20161-38617

Product information

Catalog No.
PG-20161-38617
Product Name
DBCO-PEG8-Val-Cit-PAB-Exatecan
CAS No.
Not specified
Molecular Formula
C81H99FN10O20
Molecular Weight
1551.7
Purity
95%
Storage
-20°C
Shipping
Ambient Temperature
Documents

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General Information

Product Name
DBCO-PEG8-Val-Cit-PAB-Exatecan
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C81H99FN10O20
Molecular Weight
1551.7
Appearance
Not specified
Solubility
DCM, DMF, ACN
Description

DBCO-PEG8-Val-Cit-PAB-Exatecan is a linker-payload for antibody-drug conjugate (ADC) synthesis, combining an exatecan payload with a cathepsin-cleavable Val-Cit dipeptide. The DBCO group enables copper-free click reactions with azides, while the PEG8 spacer increases the molecule's water solubility. Listed under cleavable ADC linkers and exatecan payloads, it has a specified purity of 95%, with DCM, DMF, ACN listed for solubility and -20°C specified for storage.