(+)-JQ-1-PEG4-Azide

PG-20161-47010

Product information

Catalog No.
PG-20161-47010
Product Name
(+)-JQ-1-PEG4-Azide
CAS No.
Not specified
Molecular Formula
C29H37ClN8O5S
Molecular Weight
645.2
Purity
95%
Storage
-20°C
Shipping
Ambient Temperature
Documents

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General Information

Product Name
(+)-JQ-1-PEG4-Azide
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C29H37ClN8O5S
Molecular Weight
645.2
Appearance
Not specified
Solubility
DCM
Description

(+)-JQ-1-PEG4-Azide is a triazolo-diazepine compound and reversible pan-BET family inhibitor listed within the PROTAC Linkers inhibitor categories. It competes with acetyl lysine for binding to BRD4 bromodomains 1 and 2 and serves as a chemical probe for BET-mediated transcriptional regulation in oncogenesis.

The azide group participates in CuAAC and SPAAC reactions, while the PEG4 spacer enhances water solubility. The product has molecular formula C29H37ClN8O5S, molecular weight 645.2, and purity 95%; DCM is also listed as a solubility medium.