(+)JQ-1
PG-20161-75661
Product information
- Catalog No.
- PG-20161-75661
- Product Name
- (+)JQ-1
- CAS No.
- 1268524-70-4
- Molecular Formula
- C23H25ClN4O2S
- Molecular Weight
- 457
- Purity
- Not specified
- Storage
- -20°C
- Shipping
- Ambient Temperature
- Documents
Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.
Packaging & pricing
| Catalog No. | Packaging | Price (USD) | Stock | Inquiry action |
|---|---|---|---|---|
| PG-20161-75661 | 100 MG | USD 21 | In stock |
Prices are shown in USD. Final pricing, package availability and delivery are confirmed with your quotation.
General Information
- Product Name
- (+)JQ-1
- CAS No.
- 1268524-70-4
- Synonyms
- Not specified
- Molecular Formula
- C23H25ClN4O2S
- Molecular Weight
- 457
- Appearance
- Not specified
- Solubility
- Not specified
- Description
(+)JQ-1 is a triazolo-diazepine compound that acts as a potent, specific and reversible pan-BET (bromodomain and extra-terminal motif) family inhibitor. It competes with acetyl lysine for binding to BET bromodomains, with Kd values of about 50 and 90 nM for BRD4 bromodomains 1 and 2, respectively. Listed in the BET inhibitor section of the PROTAC Linkers catalog, it serves as a chemical probe for studying BET bromodomain involvement in the transcriptional regulation of oncogenesis.