mPEG4-Val-Ala-PAB

PG-20161-49605

Product information

Catalog No.
PG-20161-49605
Product Name
mPEG4-Val-Ala-PAB
CAS No.
Not specified
Molecular Formula
C25H41N3O8
Molecular Weight
511.6
Purity
98%
Storage
-20°C
Shipping
Ambient Temperature
Documents

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General Information

Product Name
mPEG4-Val-Ala-PAB
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C25H41N3O8
Molecular Weight
511.6
Appearance
Not specified
Solubility
Not specified
Description

mPEG4-Val-Ala-PAB is a cleavable ADC linker combining a hydrophilic PEG spacer, a Val-Ala dipeptide and a p-aminobenzyl (PAB) group. Its PAB benzylic alcohol provides a site for introducing reactive groups such as PNP for subsequent conjugation to drug payloads. Protease cleavage of the Val-Ala segment enables payload release through an elimination mechanism in the PAB group.