mPEG4-Val-Ala-PAB-PNP

PG-20161-58625

Product information

Catalog No.
PG-20161-58625
Product Name
mPEG4-Val-Ala-PAB-PNP
CAS No.
Not specified
Molecular Formula
C32H44N4O12
Molecular Weight
676.7
Purity
95%
Storage
-20°C
Shipping
Ambient Temperature
Documents

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Packaging & pricing

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General Information

Product Name
mPEG4-Val-Ala-PAB-PNP
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C32H44N4O12
Molecular Weight
676.7
Appearance
Not specified
Solubility
Not specified
Description

mPEG4-Val-Ala-PAB-PNP is a cleavable ADC linker combining a hydrophilic PEG spacer, a Val-Ala dipeptide, a p-aminobenzyl (PAB) group and a PNP carbonate. The activated carbonate reacts with amines on target molecules to form carbamate linkages. Protease cleavage of the Val-Ala segment triggers an elimination process within the PAB group, enabling release of an attached drug payload. The specified purity is 95%, with storage at -20°C.