N-(Azido-PEG3)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG3-acid)
PG-20161-51755
Product information
- Catalog No.
- PG-20161-51755
- Product Name
- N-(Azido-PEG3)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG3-acid)
- CAS No.
- Not specified
- Molecular Formula
- C91H154N14O28
- Molecular Weight
- 1892.3
- Purity
- Not specified
- Storage
- -20°C
- Shipping
- Ambient Temperature
- Documents
Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.
Packaging & pricing
| Catalog No. | Packaging | Price (USD) | Stock | Inquiry action |
|---|---|---|---|---|
| PG-20161-51755 | 1mg | Inquiry | In stock | |
| PG-20161-51755 | 5mg | Inquiry | In stock | |
| PG-20161-51755 | 10mg | Inquiry | In stock |
Final pricing, package availability and delivery are confirmed with your quotation.
General Information
- Product Name
- N-(Azido-PEG3)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG3-acid)
- CAS No.
- Not specified
- Synonyms
- Not specified
- Molecular Formula
- C91H154N14O28
- Molecular Weight
- 1892.3
- Appearance
- Not specified
- Solubility
- Not specified
- Description
N-(Azido-PEG3)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG3-acid) is a branched PEG linker for antibody-drug conjugate research. It combines a terminal azide for click reactions with BCN, DBCO, or alkynes and a terminal carboxylic acid for coupling to amine-bearing molecules using activators.
The Val-Cit segment is susceptible to cleavage by intracellular proteases such as Cathepsin B, enabling MMAE release through an elimination mechanism involving PAB. PEG spacers enhance water solubility, while the branched architecture provides attachment functionality for ADC construction.