ARV-393

PG-20161-59346

Product information

Catalog No.
PG-20161-59346
Product Name
ARV-393
CAS No.
2851885-95-3
Molecular Formula
C46H53ClFN9O7
Molecular Weight
898.4
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

Packaging & pricing

Packaging and pricing for PG-20161-59346
Catalog No.PackagingPrice (USD)StockInquiry action
PG-20161-593461 MGUSD 115In stock
PG-20161-593465 MGUSD 287In stock
PG-20161-5934610 MGUSD 459In stock

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General Information

Product Name
ARV-393
CAS No.
2851885-95-3
Synonyms
Not specified
Molecular Formula
C46H53ClFN9O7
Molecular Weight
898.4
Appearance
Not specified
Solubility
Not specified
Description

ARV-393 is an orally bioavailable PROTAC designed to recruit BCL6 and the E3 ligase cereblon, promoting BCL6 degradation through the ubiquitin-proteasome pathway. Preclinical findings include activity in diffuse large B-cell lymphoma and Burkitt lymphoma cell lines, as well as tumor suppression in xenograft models. This reagent-grade compound is intended for laboratory research only and is listed in the BCL degrader category.