1,2-DOPE-C8 (10mg/ml solution in ethanol)

PG-20161-60619

Product information

Catalog No.
PG-20161-60619
Product Name
1,2-DOPE-C8 (10mg/ml solution in ethanol)
CAS No.
3081750-70-8
Molecular Formula
C52H98NO10P
Molecular Weight
928.3
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

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General Information

Product Name
1,2-DOPE-C8 (10mg/ml solution in ethanol)
CAS No.
3081750-70-8
Synonyms
Not specified
Molecular Formula
C52H98NO10P
Molecular Weight
928.3
Appearance
Not specified
Solubility
Not specified
Description

1,2-DOPE-C8 (10mg/ml solution in ethanol) is a zwitterionic glycerophospholipid cataloged under phosphatidylethanolamine helper lipids and phospholipids. DOPE-C8 has been used in lipid nanoparticles (LNPs) for in vivo mRNA delivery.

LNPs containing DOPE-C8 have shown greater endosomal escape than LNPs containing 1,2-DSPC. In mice, DOPE-C8-containing LNPs carrying mRNA encoding EGFP induced hepatic EGFP expression. These findings concern the tested LNP formulations rather than the lipid solution alone. The specified storage temperature is -20°C.