Amine-PEG8-Val-Cit-PAB-MMAE

PG-20161-72316

Product information

Catalog No.
PG-20161-72316
Product Name
Amine-PEG8-Val-Cit-PAB-MMAE
CAS No.
Not specified
Molecular Formula
C77H131N11O21
Molecular Weight
1547
Purity
98%
Storage
-20°C
Shipping
Ambient Temperature
Documents

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General Information

Product Name
Amine-PEG8-Val-Cit-PAB-MMAE
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C77H131N11O21
Molecular Weight
1547
Appearance
Not specified
Solubility
DMSO, DMF
Description

Amine-PEG8-Val-Cit-PAB-MMAE is a cleavable ADC linker–payload compound combining a primary amine, a hydrophilic PEG spacer and an enzyme-cleavable Val-Cit-PAB motif attached to MMAE. The primary amine supports amide formation with carboxylic acids using activators such as HATU or EDC. Enzymatic cleavage of the linker enables MMAE release. The compound is listed as soluble in DMSO and DMF, with purity of 98% and storage at -20°C.