MS177

PG-20161-84882

Product information

Catalog No.
PG-20161-84882
Product Name
MS177
CAS No.
2225938-86-1
Molecular Formula
C48H55N11O8
Molecular Weight
914
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

Packaging & pricing

Packaging and pricing for PG-20161-84882
Catalog No.PackagingPrice (USD)StockInquiry action
PG-20161-848825 MGUSD 216In stock
PG-20161-8488210 MGUSD 126In stock
PG-20161-8488225 MGUSD 240In stock

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General Information

Product Name
MS177
CAS No.
2225938-86-1
Synonyms
Not specified
Molecular Formula
C48H55N11O8
Molecular Weight
914
Appearance
Not specified
Solubility
Not specified
Description

MS177 is a PROTAC EZH2 degrader that combines a CRBN ligand, a linker and an EZH2 inhibitor. It targets canonical EZH2–PRC2 and noncanonical EZH2–cMyc complexes. In leukemia cells, its reported effects include inhibition of cell growth, induction of apoptosis and cell-cycle arrest.

This reagent-grade compound is intended for laboratory research only. Its molecular formula is C48H55N11O8, with a listed molecular weight of 914 and storage at -20°C.