N-(Mal-C6-carbonyl)-N-bis(PEG8-Val-Cit-PAB-MMAE)

PG-20161-91449

Product information

Catalog No.
PG-20161-91449
Product Name
N-(Mal-C6-carbonyl)-N-bis(PEG8-Val-Cit-PAB-MMAE)
CAS No.
Not specified
Molecular Formula
C164H270N22O45
Molecular Weight
3270.1
Purity
95%
Storage
-20°C
Shipping
Ambient Temperature
Documents

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General Information

Product Name
N-(Mal-C6-carbonyl)-N-bis(PEG8-Val-Cit-PAB-MMAE)
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C164H270N22O45
Molecular Weight
3270.1
Appearance
Not specified
Solubility
DCM, DMF
Description

N-(Mal-C6-carbonyl)-N-bis(PEG8-Val-Cit-PAB-MMAE) is a branched ADC linker–payload compound bearing two identical MMAE payloads. MMAE inhibits tubulin polymerization, disrupting cell division. The maleimide group supports selective reaction with thiols for site-specific modification, while the PEG component contributes aqueous solubility, biocompatibility and flexibility. Listed among dual-payload ADC linkers with the same payloads, this compound has a molecular formula of C164H270N22O45 and a specified purity of 95%.