N-(Mal)-N-bis(PEG8-Val-Cit-PAB-MMAE)

PG-20161-33461

Product information

Catalog No.
PG-20161-33461
Product Name
N-(Mal)-N-bis(PEG8-Val-Cit-PAB-MMAE)
CAS No.
Not specified
Molecular Formula
C161H264N22O45
Molecular Weight
3228
Purity
95%
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

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General Information

Product Name
N-(Mal)-N-bis(PEG8-Val-Cit-PAB-MMAE)
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C161H264N22O45
Molecular Weight
3228
Appearance
Not specified
Solubility
DMF
Description

N-(Mal)-N-bis(PEG8-Val-Cit-PAB-MMAE) is a two-branched PEG linker carrying two MMAE payloads for ADC research. Each branch includes a cathepsin-cleavable Val-Cit dipeptide and a cytotoxic MMAE unit. A terminal maleimide enables conjugation to cysteine residues on biomolecules, including monoclonal antibodies.

The PEG chains increase the compound’s water solubility. Cataloged as a cleavable, same-payload dual linker, it has a molecular weight of 3228 and a listed purity of 95%. DMF is the specified solubility medium, and the listed storage temperature is -20°C.