(2S)-3-amido-(m-PEG12)-2-maleimido-acid-(Val-Cit-PAB-MMAE)
PG-20161-93915
Product information
- Catalog No.
- PG-20161-93915
- Product Name
- (2S)-3-amido-(m-PEG12)-2-maleimido-acid-(Val-Cit-PAB-MMAE)
- CAS No.
- Not specified
- Molecular Formula
- C91H150N12O28
- Molecular Weight
- 1860.3
- Purity
- Not specified
- Storage
- -20°C
- Shipping
- Ambient Temperature
- Documents
Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.
Packaging & pricing
| Catalog No. | Packaging | Price (USD) | Stock | Inquiry action |
|---|---|---|---|---|
| PG-20161-93915 | Please advise | Inquiry | In stock |
Final pricing, package availability and delivery are confirmed with your quotation.
General Information
- Product Name
- (2S)-3-amido-(m-PEG12)-2-maleimido-acid-(Val-Cit-PAB-MMAE)
- CAS No.
- Not specified
- Synonyms
- Not specified
- Molecular Formula
- C91H150N12O28
- Molecular Weight
- 1860.3
- Appearance
- Not specified
- Solubility
- Not specified
- Description
(2S)-3-amido-(m-PEG12)-2-maleimido-acid-(Val-Cit-PAB-MMAE) is a branched maleimide-Val-Cit-PAB-MMAE linker-payload within the ADC linkers and cleavable Val-Cit-MMAE categories. The maleimide moiety reacts with antibody thiol groups, while the PEG12 side chain is reported to reduce aggregation and accelerate maleimide ring-opening hydrolysis for improved DAR stability. It incorporates the cytotoxic MMAE payload.