(2S)-3-amido-(m-PEG8)-2-maleimido-acid-(Val-Cit-PAB-MMAE)

PG-20161-38892

Product information

Catalog No.
PG-20161-38892
Product Name
(2S)-3-amido-(m-PEG8)-2-maleimido-acid-(Val-Cit-PAB-MMAE)
CAS No.
Not specified
Molecular Formula
C83H134N12O24
Molecular Weight
1684.1
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

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Packaging & pricing

Packaging and pricing for PG-20161-38892
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General Information

Product Name
(2S)-3-amido-(m-PEG8)-2-maleimido-acid-(Val-Cit-PAB-MMAE)
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C83H134N12O24
Molecular Weight
1684.1
Appearance
Not specified
Solubility
Not specified
Description

(2S)-3-amido-(m-PEG8)-2-maleimido-acid-(Val-Cit-PAB-MMAE) is a branched maleimide-containing linker-payload molecule in the cleavable ADC linker and MMAE payload categories. Its maleimide group reacts with antibody thiol groups, providing a site for conjugation.

The PEG8 side chain helps reduce aggregation and accelerates maleimide ring-opening hydrolysis, supporting drug-to-antibody ratio (DAR) stability. The compound has molecular formula C83H134N12O24 and molecular weight 1684.1. Store at -20°C.