SPDP-Val-Cit-PAB-PNP
PG-20161-94436
Product information
- Catalog No.
- PG-20161-94436
- Product Name
- SPDP-Val-Cit-PAB-PNP
- CAS No.
- Not specified
- Molecular Formula
- C33H39N7O9S2
- Molecular Weight
- 741.8
- Purity
- 98%
- Storage
- -20°C
- Shipping
- Ambient Temperature
- Documents
Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.
Packaging & pricing
| Catalog No. | Packaging | Price (USD) | Stock | Inquiry action |
|---|---|---|---|---|
| PG-20161-94436 | 5 MG | Inquiry | In stock | |
| PG-20161-94436 | 10 MG | Inquiry | In stock | |
| PG-20161-94436 | 25 MG | Inquiry | In stock |
Final pricing, package availability and delivery are confirmed with your quotation.
General Information
- Product Name
- SPDP-Val-Cit-PAB-PNP
- CAS No.
- Not specified
- Synonyms
- Not specified
- Molecular Formula
- C33H39N7O9S2
- Molecular Weight
- 741.8
- Appearance
- Not specified
- Solubility
- DMSO, DCM, DMF
- Description
SPDP-Val-Cit-PAB-PNP is a cleavable ADC linker containing an SPDP group, a Val-Cit dipeptide segment, a para-aminobenzyl spacer, and a para-nitrophenyl carbonate moiety. It is classified under ADC cleavable Val-Cit linkers and PEG linker SPDP peptide products. The SPDP component reacts with thiol groups to form disulfide bonds with protein cysteines. Val-Cit-PAB acts as a protease-cleavable unit intended for payload release upon proteolysis, and the PNP carbonate serves as a leaving group activated toward nucleophilic attack by amines.