Azide-PEG4-Val-Cit-PAB-Exatecan

PG-20161-95775

Product information

Catalog No.
PG-20161-95775
Product Name
Azide-PEG4-Val-Cit-PAB-Exatecan
CAS No.
Not specified
Molecular Formula
C54H68FN11O14
Molecular Weight
1114.2
Purity
95%
Storage
-20°C
Shipping
Ambient Temperature
Documents

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General Information

Product Name
Azide-PEG4-Val-Cit-PAB-Exatecan
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C54H68FN11O14
Molecular Weight
1114.2
Appearance
Not specified
Solubility
Not specified
Description

Azide-PEG4-Val-Cit-PAB-Exatecan is an enzymatically cleavable linker-payload conjugate for antibody-drug conjugate synthesis, classified under ADC linkers. The Val-Cit dipeptide sequence is selectively cleaved by cathepsin B, and exatecan is a camptothecin analog with anticancer activity. The terminal azide group participates in click chemistry reactions with alkyne, BCN, and DBCO.