PROTAC EGFR degrader 11
PG-20161-99453
Product information
- Catalog No.
- PG-20161-99453
- Product Name
- PROTAC EGFR degrader 11
- CAS No.
- 3034244-71-5
- Molecular Formula
- C49H64ClFN10O7S
- Molecular Weight
- 991.6
- Purity
- Not specified
- Storage
- -20°C
- Shipping
- Ambient Temperature
- Documents
Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.
Packaging & pricing
| Catalog No. | Packaging | Price (USD) | Stock | Inquiry action |
|---|---|---|---|---|
| PG-20161-99453 | 1 MG | USD 574 | In stock | |
| PG-20161-99453 | 5 MG | USD 1,855 | In stock |
Prices are shown in USD. Final pricing, package availability and delivery are confirmed with your quotation.
General Information
- Product Name
- PROTAC EGFR degrader 11
- CAS No.
- 3034244-71-5
- Synonyms
- Not specified
- Molecular Formula
- C49H64ClFN10O7S
- Molecular Weight
- 991.6
- Appearance
- Not specified
- Solubility
- Not specified
- Description
PROTAC EGFR degrader 11 is a PROTAC degrader targeting epidermal growth factor receptor (EGFR), with a reported DC50 below 100 nM. It binds CRBN-DDB1 with a Ki of 36 nM and degrades EGFR, focal adhesion kinase (FAK), and RSK1. It also inhibits proliferation of BaF3 wild-type and EGFR mutant cells with IC50 values below 100 nM. The product is stored at -20°C.