C14-A1 (solution in ethanol)

PG-20161-16232

Product information

Catalog No.
PG-20161-16232
Product Name
C14-A1 (solution in ethanol)
CAS No.
Not specified
Molecular Formula
C86H177N5O5
Molecular Weight
1361.4
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

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General Information

Product Name
C14-A1 (solution in ethanol)
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C86H177N5O5
Molecular Weight
1361.4
Appearance
Not specified
Solubility
Not specified
Description

C14-A1 (solution in ethanol) is an ionizable cationic lipid used in lipid nanoparticle (LNP) research for mRNA delivery. It is cataloged among branched, multi chargeable lipids. LNPs containing this lipid and mRNA encoding forkhead box protein P3 (FOXP3) have been reported to increase FOXP3 expression in primary human T cells. These formulations also suppress primary human CD4+/CD8+ T-cell proliferation, increase TGF-β1 secretion, and decrease IL-10 secretion from those cells.