Idasanutlin

PG-20161-16275

Product information

Catalog No.
PG-20161-16275
Product Name
Idasanutlin
CAS No.
1229705-06-9
Molecular Formula
C31H29Cl2F2N3O4
Molecular Weight
616.5
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

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Packaging & pricing

Packaging and pricing for PG-20161-16275
Catalog No.PackagingPrice (USD)StockInquiry action
PG-20161-1627550 MGUSD 67In stock
PG-20161-16275100 MGUSD 89In stock
PG-20161-16275250 MGUSD 187In stock
PG-20161-16275500 MGUSD 1,396In stock

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General Information

Product Name
Idasanutlin
CAS No.
1229705-06-9
Synonyms
Not specified
Molecular Formula
C31H29Cl2F2N3O4
Molecular Weight
616.5
Appearance
Not specified
Solubility
Not specified
Description

Idasanutlin is an MDM2 inhibitor with IC50 = 6 nM in a binding assay and 30 nM in a cancer cell proliferation assay. It induces p53 stabilization, cell cycle arrest, and apoptosis. Tumor growth inhibition has been reported in the SJSA1 tumor xenograft model, while MDR-1 inhibition occurs at high concentrations. It is cataloged in the MDM2 inhibitor section under PROTAC Linkers.