DMA4-H228 (10mg/ml solution in ethanol)

PG-20161-36810

Product information

Catalog No.
PG-20161-36810
Product Name
DMA4-H228 (10mg/ml solution in ethanol)
CAS No.
3091917-64-2
Molecular Formula
C57H106N4O10
Molecular Weight
1007.5
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

Packaging & pricing

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General Information

Product Name
DMA4-H228 (10mg/ml solution in ethanol)
CAS No.
3091917-64-2
Synonyms
Not specified
Molecular Formula
C57H106N4O10
Molecular Weight
1007.5
Appearance
Not specified
Solubility
Not specified
Description

DMA4-H228 (10mg/ml solution in ethanol) is an ionizable cationic lipidoid used to prepare lipid nanoparticles (LNPs) for in vivo mRNA delivery. It is cataloged in the ionizable lipid section of Lipid-PEG.

In a B16/F10-OVA murine melanoma model, LNPs containing DMA4-H228 and ovalbumin-encoding mRNA were associated with reduced tumor volume, increased intratumoral CD8+ T cells, and higher serum anti-ovalbumin IgG titers. The listed storage temperature is -20°C.