Mal-amido-PEG2-Val-Cit-PAB-PNP

PG-20161-41190

Product information

Catalog No.
PG-20161-41190
Product Name
Mal-amido-PEG2-Val-Cit-PAB-PNP
CAS No.
2112738-13-1
Molecular Formula
C39H50N8O14
Molecular Weight
854.9
Purity
98%
Storage
-20°C
Shipping
Ambient Temperature
Documents

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Packaging & pricing

Packaging and pricing for PG-20161-41190
Catalog No.PackagingPrice (USD)StockInquiry action
PG-20161-4119025 MGUSD 391In stock
PG-20161-4119050 MGUSD 748In stock
PG-20161-41190100 MGUSD 1,282In stock
PG-20161-41190250 MGUSD 2,243In stock

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General Information

Product Name
Mal-amido-PEG2-Val-Cit-PAB-PNP
CAS No.
2112738-13-1
Synonyms
Not specified
Molecular Formula
C39H50N8O14
Molecular Weight
854.9
Appearance
Not specified
Solubility
DMSO, DCM, DMF
Description

Mal-amido-PEG2-Val-Cit-PAB-PNP is a cleavable ADC linker combining a maleimide group, a hydrophilic PEG spacer, a valine-citrulline (Val-Cit) dipeptide, a para-aminobenzyl (PAB) spacer and a para-nitrophenyl (PNP) carbonate. The maleimide enables covalent labeling of protein cysteine thiols, while the activated PNP carbonate provides a site for reaction with amines.

The Val-Cit-PAB segment supports peptidase-mediated cleavage for payload release in ADC designs. The product has a molecular formula of C39H50N8O14 and a listed purity of 98%. Listed solvents are DMSO, DCM, DMF, with storage at -20°C.