ALV1

PG-20161-53223

Product information

Catalog No.
PG-20161-53223
Product Name
ALV1
CAS No.
2438124-79-7
Molecular Formula
C25H23ClN4O5
Molecular Weight
494.9
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

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Packaging & pricing

Packaging and pricing for PG-20161-53223
Catalog No.PackagingPrice (USD)StockInquiry action
PG-20161-532235 MGUSD 147In stock
PG-20161-5322310 MGUSD 257In stock
PG-20161-5322325 MGUSD 513In stock
PG-20161-5322350 MGUSD 789In stock

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General Information

Product Name
ALV1
CAS No.
2438124-79-7
Synonyms
Not specified
Molecular Formula
C25H23ClN4O5
Molecular Weight
494.9
Appearance
Not specified
Solubility
Not specified
Description

ALV1 is a molecular glue degrader targeting Ikaros (IKZF1) and Helios (IKZF2), with reported DC50 values of 2.5 nM and 10.3 nM, respectively. It binds CRBN with an IC50 of 0.55 µM and induces CRBN-Helios dimerization. Listed among IKZF degraders, ALV1 is used in research on regulatory T-cell properties and functions. The specified storage temperature is -20°C.