LLC0424

PG-20161-62857

Product information

Catalog No.
PG-20161-62857
Product Name
LLC0424
CAS No.
3061315-33-8
Molecular Formula
C45H41N7O9
Molecular Weight
823.9
Purity
Not specified
Storage
-20°C
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Ambient Temperature
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Packaging and pricing for PG-20161-62857
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PG-20161-628571 MGUSD 627In stock

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General Information

Product Name
LLC0424
CAS No.
3061315-33-8
Synonyms
Not specified
Molecular Formula
C45H41N7O9
Molecular Weight
823.9
Appearance
Not specified
Solubility
Not specified
Description

LLC0424 is a cereblon-based PROTAC degrader targeting nuclear receptor-binding SET domain-containing 2 (NSD2). In RPMI-8402 cells, it induced NSD2 degradation with a DC50 of 20 nM. This selective degradation depends on both cereblon and the proteasome. Cataloged among NSD2 degraders, the compound has the molecular formula C45H41N7O9 and a listed molecular weight of 823.9. Storage is specified at -20°C.