NHS-PEG4-GGFG-DXD

PG-20161-69477

Product information

Catalog No.
PG-20161-69477
Product Name
NHS-PEG4-GGFG-DXD
CAS No.
Not specified
Molecular Formula
C58H68FN9O19
Molecular Weight
1214.2
Purity
95%
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

Packaging & pricing

Packaging and pricing for PG-20161-69477
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PG-20161-694771 MGInquiryIn stock
PG-20161-694775 MGInquiryIn stock
PG-20161-6947710 MGInquiryIn stock
PG-20161-6947725 MGInquiryIn stock

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General Information

Product Name
NHS-PEG4-GGFG-DXD
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C58H68FN9O19
Molecular Weight
1214.2
Appearance
Not specified
Solubility
DMSO, DMF
Description

NHS-PEG4-GGFG-DXD is a tetrapeptide linker-payload for antibody-drug conjugate (ADC) preparation. It combines an amine-reactive NHS group with a PEG4 segment, an intracellularly protease-cleavable GGFG sequence, and DXD. The DXD payload is an Exatecan derivative that inhibits DNA topoisomerase I, while the PEG4 segment supports aqueous solubility. The product has a molecular formula of C58H68FN9O19 and a listed purity of 95%; DMSO and DMF are specified as solvents.