NHS ester-PEG8-GGFG-DXD

PG-20161-99615

Product information

Catalog No.
PG-20161-99615
Product Name
NHS ester-PEG8-GGFG-DXD
CAS No.
Not specified
Molecular Formula
C66H84FN9O23
Molecular Weight
1390.5
Purity
90%
Storage
-20°C
Shipping
Ambient Temperature
Documents

Missing values are marked “Not specified”. Request the technical information you need with your inquiry. For research use only.

Packaging & pricing

Packaging and pricing for PG-20161-99615
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General Information

Product Name
NHS ester-PEG8-GGFG-DXD
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C66H84FN9O23
Molecular Weight
1390.5
Appearance
Not specified
Solubility
Not specified
Description

NHS ester-PEG8-GGFG-DXD is a tetrapeptide linker-payload compound listed under ADC Linkers and ADC Payload categories. Its NHS ester group reacts with amine moieties, enabling conjugation to antibodies for antibody-drug conjugate (ADC) development. The construct incorporates a GGFG protease-cleavable peptide, a PEG8 segment, and DXD, a derivative of Exatecan that acts as a DNA topoisomerase I inhibitor payload.