Bis-sulfone-PEG4-NHS Ester

PG-20161-74136

Product information

Catalog No.
PG-20161-74136
Product Name
Bis-sulfone-PEG4-NHS Ester
CAS No.
2055047-19-1
Molecular Formula
C40H48N2O14S2
Molecular Weight
845
Purity
93%
Storage
-20°C
Shipping
Ambient Temperature
Documents

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Packaging & pricing

Packaging and pricing for PG-20161-74136
Catalog No.PackagingPrice (USD)StockInquiry action
PG-20161-74136100 MGUSD 1,100In stock
PG-20161-7413625 MGUSD 449In stock

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General Information

Product Name
Bis-sulfone-PEG4-NHS Ester
CAS No.
2055047-19-1
Synonyms
Not specified
Molecular Formula
C40H48N2O14S2
Molecular Weight
845
Appearance
Not specified
Solubility
DMSO, DCM, DMF
Description

Bis-sulfone-PEG4-NHS Ester is a bis-alkylating labeling reagent used for site-specific conjugation at reduced native disulfides, including antibody interchain disulfides. It reacts with both cysteine thiols generated by reduction, forming a covalent three carbon bridge that rebridges the cysteine pair while retaining protein structural integrity. The hydrophilic PEG spacer increases solubility in aqueous media. It is cataloged among ADC linkers and PEG NHS esters.