Bis-sulfone-PEG12-NHS Ester

PG-20161-86256

Product information

Catalog No.
PG-20161-86256
Product Name
Bis-sulfone-PEG12-NHS Ester
CAS No.
2055105-51-4
Molecular Formula
C56H80N2O22S2
Molecular Weight
1197.4
Purity
90%
Storage
-20°C
Shipping
Ambient Temperature
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Packaging & pricing

Packaging and pricing for PG-20161-86256
Catalog No.PackagingPrice (USD)StockInquiry action
PG-20161-8625650 MGUSD 2,168In stock
PG-20161-86256100 MGUSD 3,094In stock
PG-20161-86256250 MGUSD 6,188In stock

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General Information

Product Name
Bis-sulfone-PEG12-NHS Ester
CAS No.
2055105-51-4
Synonyms
Not specified
Molecular Formula
C56H80N2O22S2
Molecular Weight
1197.4
Appearance
Not specified
Solubility
DMSO, DCM, DMF
Description

Bis-sulfone-PEG12-NHS Ester is a bis-alkylating labeling reagent for conjugating the two cysteine thiols generated by reduction of a native disulfide bond, including antibody interchain disulfides. Selective reaction at the cysteine sulfur atoms creates a covalent three carbon bridge, rebridging the reduced disulfide while retaining the protein's structural integrity.

The hydrophilic PEG spacer increases solubility in aqueous media. Listed under site-specific ADC linkers and PEG NHS ester linkers, this reagent has a specified purity of 90% and is soluble in DMSO, DCM, DMF.