Bis-sulfone-PEG8-NHS Ester

PG-20161-92407

Product information

Catalog No.
PG-20161-92407
Product Name
Bis-sulfone-PEG8-NHS Ester
CAS No.
2363757-66-6
Molecular Formula
C48H64N2O18S2
Molecular Weight
1021.2
Purity
95%
Storage
-20°C
Shipping
Ambient Temperature
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General Information

Product Name
Bis-sulfone-PEG8-NHS Ester
CAS No.
2363757-66-6
Synonyms
Not specified
Molecular Formula
C48H64N2O18S2
Molecular Weight
1021.2
Appearance
Not specified
Solubility
Not specified
Description

Bis-sulfone-PEG8-NHS Ester is a bis-alkylating PEG labeling reagent used for conjugation at cysteine sulfur atoms obtained by reducing a native disulfide bond. It reacts with both resulting thiols, including those from antibody interchain disulfides, to create a covalent three carbon bridge while retaining the protein's structural integrity.

The hydrophilic PEG spacer increases solubility in aqueous media. This reagent is cataloged among site-specific ADC linkers and PEG NHS ester linkers, with a specified purity of 95%.