Azido-PEG8-Val-Cit-PAB-OH

PG-20161-78351

Product information

Catalog No.
PG-20161-78351
Product Name
Azido-PEG8-Val-Cit-PAB-OH
CAS No.
Not specified
Molecular Formula
C37H64N8O13
Molecular Weight
829
Purity
98%
Storage
-20°C
Shipping
Ambient Temperature
Documents

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Packaging & pricing

Packaging and pricing for PG-20161-78351
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PG-20161-78351100 MGInquiryIn stock
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General Information

Product Name
Azido-PEG8-Val-Cit-PAB-OH
CAS No.
Not specified
Synonyms
Not specified
Molecular Formula
C37H64N8O13
Molecular Weight
829
Appearance
Not specified
Solubility
Water, DMSO, DMF
Description

Azido-PEG8-Val-Cit-PAB-OH is a cleavable linker intermediate containing an azide, a hydrophilic PEG spacer, a Val-Cit dipeptide and a PAB group. The azide supports click reactions with terminal alkynes or strained cyclooctynes such as DBCO or BCN. Cellular protease cleavage of Val-Cit enables subsequent payload release through an elimination mechanism involving PAB. Cataloged among cleavable ADC linkers, it has listed solubility in Water, DMSO, DMF.