NX-5948

PG-20161-79199

Product information

Catalog No.
PG-20161-79199
Product Name
NX-5948
CAS No.
2649400-34-8
Molecular Formula
C42H54N12O5
Molecular Weight
807
Purity
Not specified
Storage
-20°C
Shipping
Ambient Temperature
Documents

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Packaging & pricing

Packaging and pricing for PG-20161-79199
Catalog No.PackagingPrice (USD)StockInquiry action
PG-20161-791991 MGUSD 61In stock
PG-20161-791995 MGUSD 123In stock

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General Information

Product Name
NX-5948
CAS No.
2649400-34-8
Synonyms
Not specified
Molecular Formula
C42H54N12O5
Molecular Weight
807
Appearance
Not specified
Solubility
Not specified
Description

NX-5948 is an orally active chimeric molecule that selectively targets BTK for degradation through the cereblon E3 ligase complex. Reported preclinical activities include inhibition of B cell activation, reduced tumor growth in xenograft models, activity in collagen-induced arthritis models, and blood-brain barrier penetration. It is cataloged among BTK degraders within the PROTAC Linkers category and is intended for laboratory research only.